Author: Sophie
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Emergent Mechanisms in Biocatalysis
Felix C. Raps and Todd K. Hyster ACS Cent. Sci. 2025, 11, 7, 1029–1040
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Synergistic Photoenzymatic Anti-Markovnikov Hydroarylation of Olefins via Heteroaryl Radical Intermediates
Prasun Mukherjee, Zayed Alassad, Todd K. Hyster J. Am. Chem. Soc. 2025, 147, 17, 14048–14053.
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Unique Electron Donor–Acceptor Complex Conformation Ensures Both the Efficiency and Enantioselectivity of Photoinduced Radical Cyclization in a Non-natural Photoenzyme
Matteo Capone, Gianluca Dell’Orletta, Claire G. Page, Todd K. Hyster, Gregory D. Scholes, Isabella Daidone ACS Catal. 2024, 14, 16488-16496.
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Engineering a photoenzyme to use red light
Jose M. Carceller, Bhumika Jayee, Claire G. Page, Daniel G. Oblinsky, Gustavo Mondragón-Solórzano, Nithin Chintala, Jingzhe Cao, Zayed Alassad, Zheyu Zhang, Nathaniel White, Danny J. Diaz, Andrew D. Ellington, Gregory D. Scholes, Sijia S. Dong, Todd K. Hyster Chem 2025, 11, 1-11.
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Emergence of a distinct mechanism of C–N bond formation in photoenzymes
Felix C. Raps, Ariadna Rivas-Souchet, Chey M. Jones, Todd K. Hyster Nature, 2025, 637, 362-368
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Synergistic Photoenzymatic Catalysis Enables Synthesis of a-Tertiary Amino Acids Using Threonine Aldolases
Yao Ouyang, Claire Page, Catherine Bliodeau, Todd K. Hyster J. Am. Chem. Soc. 2024, 146, 20, 13754–13759.
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From Ground-State to Excited-State Activation Modes: Flavin-Dependent “Ene”-Reductases Catalyzed Non-natural Radical Reactions
Haigen Fu and Todd K. Hyster Acc. Chem. Res. 2024, 57, 9, 1446–1457.
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Carolyn Guan
she/her Princeton UniversityA.B. Chemistry, 2020 Johns Hopkins University School of MedicineMedical Student
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Shirley Klimkiewicz
she/her Princeton UniversityA.B. Chemistry, 2020 Johns Hopkins University Applied Physics LaboratoryChemist
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Natalie Bahrami
she/her Princeton UniversityA.B. Chemistry, 2021 Blackstone Life SciencesAssociate