Category: Publications
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Synthesis of 𝛽-Quaternary Lactams Using Photoenzymatic Catalysis
Joshua R. Turek-Herman, Mike Rosenberger, Todd K. Hyster Asian J. Org. Chem. 2023, 12 (8), e202300274
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Mechanism and Dynamics of Photodecarboxylation Catalyzed by Lactate Monooxygenase
Xiankun Li, Claire G. Page, Laura Zanetti-Polzi, Aarat P. Kalra, Daniel G. Oblinsky, Isabella Daidone, Todd K. Hyster, and Gregory D. Scholes J. Am. Chem. Soc. 2023, 145, 24, 13232-13240
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Regioselective Radical Alkylation of Arenes Using Evolved Photoenzymes
Claire G. Page, Jingzhe Cao, Daniel G. Oblinsky, Samantha N. MacMillan, Shiva Dahagam, Ruth M. Lloyd, Simon J. Charnock, Gregory D. Scholes, and Todd K. Hyster J. Am. Chem. Soc. 2023, 145, 21, 11866-11874
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Photobiocatalytic Strategies for Organic Synthesis
Megan A. Emmanuel, Sophie G. Bender, Catherine Bilodeau, Jose M. Carceller, Jacob S. DeHovitz, Haigen Fu, Yi Liu, Bryce T. Nicholls, Yao Ouyang, Claire G. Page, Tianzhang Qiao, Felix C. Raps, Damien R. Sorigué, Shang-Zheng Sun, Joshua Turek-Herman, Yuxuan Ye, Ariadna Rivas-Souchet, Jingzhe Cao, and Todd K. Hyster Chem. Rev. 2023, 123, 9, 5459-5520
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Asymmetric C-Alkylation of Nitroalkanes via Enzymatic Photoredox Catalysis
Haigen Fu, Tianzhang Qiao, Jose M. Carceller, Samantha N. MacMillan, and Todd K. Hyster J. Am. Chem. Soc. 2023, 145, 2, 787-793
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Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination
Yuxuan Ye, Jingzhe Cao, Daniel G. Oblinsky, Deeptak Verma, Christopher K. Prier, Gregory D. Scholes, and Todd K. Hyster Nat. Chem. 2023, 15, 206-212
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Photoenzymatic Catalysis in a New Light: Gluconobacter “Ene”-Reductase Conjugates Possessing High-Energy Reactivity with Tunable Low-Energy Excitation
Paul T. Cesana, Claire G. Page, Dvir Harris, Megan A. Emmanuel, Todd K. Hyster, and Gabriela S. Schlau-Cohen J. Am. Chem. Soc. 2022, 144, 38, 17516-17521
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An asymmetric sp³–sp³ cross-electrophile coupling using ‘ene’-reductases
Haigen Fu, Jingzhe Cao, Tianzhang Qiao, Yuyin Qi, Simon J. Charnock, Samuel Garfinkle, and Todd K. Hyster Nature 2022, 610, 302-307
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Radical Termination via β-Scission Enables Photoenzymatic Allylic Alkylation Using “Ene”-Reductases
Netgie Laguerre, Paul S. Riehl, Daniel G. Oblinsky, Megan A. Emmanuel, Michael J. Black, Gregory D. Scholes, and Todd K. Hyster ACS Catal. 2022, 12, 15, 9801-9805
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Photoinduced Dynamic Radical Processes for Isomerizations, Deracemizations, and Dynamic Kinetic Resolutions
Jacob S. DeHovitz and Todd K. Hyster ACS Catal. 2022, 12, 15, 8911-8924