Category: Publications
-
Emergence of a distinct mechanism of C–N bond formation in photoenzymes
Felix C. Raps, Ariadna Rivas-Souchet, Chey M. Jones, Todd K. Hyster Nature, 2025, 637, 362-368
-
Synergistic Photoenzymatic Catalysis Enables Synthesis of a-Tertiary Amino Acids Using Threonine Aldolases
Yao Ouyang, Claire Page, Catherine Bliodeau, Todd K. Hyster J. Am. Chem. Soc. 2024, 146, 20, 13754–13759.
-
From Ground-State to Excited-State Activation Modes: Flavin-Dependent “Ene”-Reductases Catalyzed Non-natural Radical Reactions
Haigen Fu and Todd K. Hyster Acc. Chem. Res. 2024, 57, 9, 1446–1457.
-
Asymmetric Synthesis of 𝛼-Chloroamides via Photoenzymatic Hydroalkylation of Olefins
Yi Liu, Sophie G. Bender, Damien Sorigue, Daniel J. Diaz, Andrew D. Ellington, Greg Mann, Simon Allmendinger, and Todd K. Hyster J. Am. Chem. Soc. 2024, 146, 11, 7191–7197
-
Regiodivergent Radical Termination for Intermolecular Biocatalytic C–C Bond Formation
Mark R. Petchey, Yuxuan Ye, Victor Spelling, James D. Finnigan, Samantha Gittings, Magnus J. Johansson, Martin A. Hayes, and Todd K. Hyster J. Am. Chem. Soc. 2024, 146, 7, 5005-5010
-
Enantioselective decarboxylative alkylation using synergistic photoenzymatic catalysis
Shang-Zheng Sun, Bryce T. Nicholls, David Bain, Tianzhang Qiao, Claire G. Page, Andrew J. Musser, and Todd K. Hyster Nat. Catal. 2024, 7, 35-42
-
Evidence of a Distinctive Enantioselective Binding Mode for the Photoinduced Radical Cyclization of 𝛼-Chloroamides in Ene-Reductases
Matteo Capone, Gianluca Dell’Orletta, Bryce T. Nicholls, Gregory D. Scholes, Todd K. Hyster, Massimiliano Aschi, Isabella Daidone ACS Catal. 2023, 13, 15310-15321
-
Pyridylmethyl Radicals for Enantioselective Alkene Hydroalkylation Using “Ene”-Reductases
Sophie G. Bender and Todd K. Hyster ACS Catal. 2023, 13, 14680–14684
-
Using Data Science for Mechanistic Insights and Selectivity Predictions in a Non-Natural Biocatalytic Reaction
Hanna D. Clements, Autumn R. Flynn, Bryce T. Nicholls, Daria Grosheva, Sarah J. Lefave, Morgan T. Merriman, Todd K. Hyster, Matthew S. Sigman J. Am. Chem. Soc. 2023, 145, 32, 17656-17664
-
Asymmetric Carbohydroxylation of Alkenes Using Photoenzymatic Catalysis
Yao Ouyang, Joshua Turek-Herman, Tianzhang Qiao, Todd K. Hyster J. Am. Chem. Soc. 2023, 145, 31, 17018-17022