Author: nw10design
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A Photoenzyme for Challenging Lactam Radical Cyclizations
Bryce T. Nicholls, Tianzhang Qiao, and Todd K. Hyster Synlett 2022, 33, 12, 1204-1208
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Photoenzymatic Synthesis of α-Tertiary Amines by Engineered Flavin-Dependent “Ene”-Reductases
Xin Gao, Joshua R. Turek-Herman, Young Joo Choi, Ryan D. Cohen, and Todd K. Hyster J. Am. Chem. Soc. 2021, 143, 47, 19643-19647
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Engineering a Non-Natural Photoenzyme for Improved Photon Efficiency
Bryce T. Nicholls, Daniel G. Oblinsky, Sarah I. Kurtoic, Daria Grosheva, Yuxuan Ye, Gregory D. Scholes, and Todd K. Hyster Angew. Chem. Int. Ed. 2022, 61, e202113842
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Ground-State Electron Transfer as an Initiation Mechanism for Biocatalytic C–C Bond Forming Reactions
Haigen Fu, Heather Lam, Megan A. Emmanuel, Ji Hye Kim, Braddock A. Sandoval, and Todd K. Hyster J. Am. Chem. Soc. 2021, 143, 25, 9622-9629
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Light-Driven Flavin-Based Biocatalysis
Daria Grosheva and Todd K. Hyster Flavin-Based Catalysis: Principles and Applications, Chapter 12
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Activation modes in biocatalytic radical cyclization reactions
Yuxuan Ye, Haigen Fu, and Todd K. Hyster J. Ind. Microbiol. Biotechnol. 2021, 48, kuab021
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Photoenzymatic Reductions Enabled by Direct Excitation of Flavin-Dependent “Ene”-Reductases
Braddock A. Sandoval, Phillip D. Clayman, Daniel G. Oblinsky, Seokjoon Oh, Yuji Nakano, Matthew Bird, Gregory D. Scholes, and Todd K. Hyster J. Am. Chem. Soc. 2021, 143, 4, 1735-1739
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Quaternary Charge-Transfer Complex Enables Photoenzymatic Intermolecular Hydroalkylation of Olefins
Claire G. Page, Simon J. Cooper, Jacob S. DeHovitz, Daniel G. Oblinsky, Kyle F. Biegasiewicz, Alyssa H. Antropow, Kurt W. Armbrust, J. Michael Ellis, Lawrence G. Hamann, Evan J. Horn, Kevin M. Oberg, Gregory D. Scholes, and Todd K. Hyster J. Am. Chem. Soc. 2021, 143, 1, 97-102
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Active-Site Environmental Factors Customize the Photophysics of Photoenzymatic Old Yellow Enzymes
Bryan Kudisch, Daniel G. Oblinsky, Michael J. Black, Anna Zieleniewska, Megan A. Emmanuel, Garry Rumbles, Todd K. Hyster, and Gregory D. Scholes J. Phys. Chem. B 2020, 124, 49, 11236-11249
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Photoenzymatic Generation of Unstabilized Alkyl Radicals: An Asymmetric Reductive Cyclization
Phillip D. Clayman and Todd K. Hyster J. Am. Chem. Soc. 2020, 142, 37, 15673-15677